Intact Nucleosomal Context Enables Chromodomain Reader MRG15 to Distinguish H3K36me3 from - Me2
نویسندگان
چکیده
منابع مشابه
Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes
Trimethylation of lysine 36 of histone H3 (H3K36me3) is found to be associated with various transcription events. In Arabidopsis, the H3K36me3 level peaks in the first half of coding regions, which is in contrast to the 3'-end enrichment in animals. The MRG15 family proteins function as 'reader' proteins by binding to H3K36me3 to control alternative splicing or prevent spurious intragenic trans...
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ژورنال
عنوان ژورنال: SSRN Electronic Journal
سال: 2020
ISSN: 1556-5068
DOI: 10.2139/ssrn.3639614